TORONTO (AP) -- Andy Roddick followed Roger Federer out of the Rogers Cup.
The sixth-seeded Roddick was upset by 44th-ranked Marin Cilic 6-4, 4-6, 6-4 on Thursday.
"His aggressiveness is what won him that match today," Roddick said. "He took it to me a lot more than I took it to him."
Defending champion Novak Djokovic advanced to the quarterfinals with a 6-4, 6-4 win over Robin Soderling.
"I played more or less at the level which was satisfying for me," Djokovic said.
Gilles Simon, who upset the top-ranked Federer on Wednesday, advanced with a 6-3, 6-4 win over Jose Acasuso.
Also, eighth-seeded Andy Murray of Britain advanced with a 6-2, 0-6, 6-4 win over ninth seed Stanislas Wawrinka of Switzerland.
Rafael Nadal, Nikolay Davydenko and David Ferrer were to play later Thursday.